CB-13
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 27 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 27 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Cra-13, Sab-378
Summary
CB-13 is designed to stay largely outside the blood–brain barrier, providing peripheral CB₁/CB₂ activity (analgesia, anti-inflammatory) with greatly reduced central psychoactivity. Recreational 'high' is weak or absent below very large doses; most user reports describe mild body relaxation, analgesia and sleepiness rather than classic cannabis effects. Because effective doses are hundreds of milligrams orally, material cost, impurities and liver load become significant concerns.
Dose Information
Dose basis. No clinical dosing guidelines; values are aggregated from community reports and small-user self-experiments. High lipophilicity suggests food/meal fat may increase exposure (inference from CBD PK; if eating with high-fat meals expect stronger effects). Users report low volatility and inefficient aerosolization; risk of thermal decomposition/pyrolysis products as with other synthetic cannabinoids; use caution and low temperatures if attempted. Avoid herbal-carrier ‘blend’ preparations due to uneven distribution (‘hot pockets’) seen with synthetic cannabinoids generally. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 75-150mg | 150-300mg | 300-450mg | 450mg+ (not recommended) |
| Vaporized | 10-15mg | 15-30mg (inefficient) | 30-50mg | 50mg+ (little additional effect) |
Sources
Oral
Dose ladder — Drugs.WikiVaporized
Dose ladder — Drugs.WikiOnset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 30-90 min | 2-4 hrs | 2-4 hrs | 4.5-9.5 hrs |
| Vaporized | 1-5 min | 30-90 min | 1-2 hrs | 1.52-3.58 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate visuals with mild headspace and auditory effects, low body load
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Based on cannabinoid-class tolerance patterns: repeated daily activation downregulates CB1 signaling with partial reversal over days to weeks. Data specific to CB‑13 in humans are lacking; values above are heuristic. Evidence quality: anecdotal and cannabinoid-class extrapolation.
Cross-Tolerances
Effects
Effect glossary — · full glossary
- Warmth/tingling
Combinations
Cross-Check CB-13 with another substanceHelpful Links
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The PsychonautWiki Journal logging app doesn't include every substance. To track CB-13 there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
CB-13 Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 50 · light 75-150 · common 150-300 · strong 300-450 · heavy 450+ (not recommended) Vaporized dose (mg): threshold 5 · light 10-15 · common 15-30 (inefficient) · strong 30-50 · heavy 50+ (little additional effect) Oral duration: onset 0.5-1.5h · peak 2-4h · offset 2-4h · total 4.5-9.5h · after-effects 2-6h Vaporized duration: onset 1-5m · peak 0.5-1.5h · offset 1-2h · total 1.52-3.58h · after-effects 2-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 225 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
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