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    Tetrahydrocannabutol Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data
    • 27 combo interactions documented

    Summary PsychonautWiki

    Tetrahydrocannabutol (THCB) is the butyl homologue of THC — the same dibenzopyran scaffold with a four-carbon side chain in place of THC's five. It occurs naturally in cannabis in trace amounts and binds CB1 with affinity comparable to THC in the limited published assays. Human data is essentially nonexistent; products sold as THCB are semi-synthetic hemp derivatives of untested purity.

    Tolerance

    Build-up develops over weeks of regular use via CB1 receptor downregulation
    Reset 2–4 weeks for most users; heavy users may need longer

    Tolerance Decay

    Full tolerance 3d Half tolerance 21d Baseline ~28d

    Effects

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Combinations

    Cross-Check Tetrahydrocannabutol with another substance

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