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    Disclaimer
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    ⚠ Opioids carry significant risk of respiratory depression, physical dependence, and fatal overdose. Never combine with other depressants.

    Spirochlorphine Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • duration data present
    • 29 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Aliases: Spc, R-6890

    Summary dose.wiki

    Marketed only as a research chemical with potency reported as 2-5 times that of fentanyl. Reported solubility approximately 3 mg/mL in 10% ethanol/PG solution. Users stress volumetric dosing and allergy testing because a 10-fold error spans the entire active range.

    Dose Information source varies by route

    Dose basis. The dose figures on this page are not clinical data. They are aggregated from community reports by a secondary source whose own notes state there is no human pharmacokinetic study behind them, and our internal audit flags this substance's dosing as unverifiable. Treat them as a rough orientation, not a safe range. This is a microgram-active opioid: a normal milligram scale cannot weigh a dose of it accurately, and a weighing error here is measured in lethal multiples rather than percentages. Volumetric dosing is the only defensible method, and batch-to-batch potency in the unregulated supply varies enormously. Assume full respiratory depression, keep naloxone to hand, never dose alone, and never combine with benzodiazepines, alcohol or other depressants.

    ROA Threshold
    Insufflated 50-100ug
    Intravenous 0.2mg

    Only a threshold dose is documented for this substance β€” the smallest amount with a noticeable effect. There is no published light/common/strong ladder to show above it.

    Sources

    Insufflated

    Dose ladder — Drugs.Wiki

    Intravenous

    Dose ladder — DrugsPRO

    Onset, Duration & After-effects dose.wiki

    ROA Onset Peak Offset After Effects Total
    Insufflated 5-15 min 30-90 min 2-4 hrs 2-6 hrs 2.58-5.75 hrs
    Intravenous 1-5 min 30-90 min 2-4 hrs 2-6 hrs 2.52-5.58 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 7.9
    Intense 8/10

    Strong euphoria and pain relief with moderate itching/nausea, mild sedation

    Euphoria / Warmth ×3
    10
    physical euphoria cognitive euphoria euphoria warmth
    Analgesia ×2
    8
    pain relief analgesia
    Sedation / Relaxation ×1
    5
    sedation muscle relaxation
    ⚠ Itching / Nausea ×1
    6
    nausea constipation

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks β€” tolerance loss greatly increases overdose risk

    Tolerance Decay

    Full tolerance 3d Half tolerance 10d Baseline ~28d

    Opioid tolerance builds quickly and decays slowly; precise rates for SPC are unknown. Cross‑tolerance with other μ‑opioids is expected by pharmacological class inference, but magnitudes are uncertain. Data quality low/anecdotal.

    Effects dose.wiki

    Positive
    Negative
    Neutral
    Positive
    Negative
    Positive
    Negative
    Neutral

    Combinations

    Cross-Check Spirochlorphine with another substance

    →

    Helpful Links

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Spirochlorphine there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    Name
    Spirochlorphine
    Unit
    Β΅g
    Description
    Spirochlorphine
    Source: SubstanceSearch (substancesearch.com)
    
    Insufflated dose (Β΅g): threshold 50-100ug
    Intravenous dose (mg): threshold 0.2
    
    Insufflated duration: onset 5-15m Β· peak 0.5-1.5h Β· offset 2-4h Β· total 2.58-5.75h Β· after-effects 2-6h
    Intravenous duration: onset 1-5m Β· peak 0.5-1.5h Β· offset 2-4h Β· total 2.52-5.58h Β· after-effects 2-6h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.