Beta test rollout. This site is in community QA — please send feature requests, bug reports and data corrections on the Feedback page or on GitHub.

Home
    Disclaimer
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Dichloropane Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 4 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • toxicity data (PsychonautWiki)
    • classified Tentative
    • classified Research-chemical

    Aliases: O-401, Rti-111

    Stimulant Research-chemical

    Summary dose.wiki TripSit PsychonautWiki

    Dichloropane is a novel research chemical with very limited human use history since its appearance around 2010. Due to structural similarity to cocaine, it may carry similar cardiovascular risks including potential for sudden cardiac death at high doses and long-term cardiomyopathy. Regular insufflation can severely damage nasal tissue, causing loss of smell, nosebleeds, and chronic nasal problems.

    Dose Information source varies by route

    ROA Light Common Strong Heavy
    Insufflated 10-20mg 20-40mg 40-60mg 60mg+
    Oral 10-15mg 15-30mg 30-50mg 50mg+
    Smoked 2.5-7.5mg 7.5-20mg 20-50mg 50mg+
    Light Common Strong Heavy
    Sources

    Insufflated

    Dose ladder — PsychonautWiki

    Oral

    Dose ladder — dose.wiki

    Smoked

    Dose ladder — dose.wiki, PsychonautWiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Insufflated 5-15 min 15-30 min 60-90 min 60-90 min 1-6 hrs 2.33-3.75 hrs
    Oral 10-30 min 30-60 min 60-90 min 60-90 min 1-6 hrs 2.67-4.5 hrs
    Smoked 0-1 min 0-1 min 15-30 min 20-40 min - 40-75 min

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 5.2
    Moderate+ 5/10

    Strong anxiety/jitters with moderate focus and stimulation, mild euphoria

    Stimulation / Energy ×3
    6
    stimulation mental stimulation alertness enhancement
    Euphoria / Mood Lift ×2
    5
    cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    7
    focus enhancement thought acceleration motivation enhancement
    ⚠ Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate tachycardia vasoconstriction
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Effects dose.wiki

    Positive
    Negative
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Dichloropane's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📘 Experience Reports 📖 dose.wiki 📖 TripSit 📖 PsychonautWiki
    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has Dichloropane, but its built-in entry only covers Insufflated, Smoked. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "Dichloropane (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Custom Unit doses
    • Oralcommon ~ 22.5 mg
    Dose & duration (reference) 
    Dichloropane: routes the PsychonautWiki Journal app is missing
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 10-15 · common 15-30 · strong 30-50 · heavy 50+

Oral duration: onset 10-30m · come-up 0.5-1h · peak 1-1.5h · offset 1-1.5h · total 2.67-4.5h · after-effects 1-6h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.