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    ⚠ Opioids carry significant risk of respiratory depression, physical dependence, and fatal overdose. Never combine with other depressants.

    Dextromoramide Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 29 combo interactions documented

    Aliases: palfium

    Depressant Opioid

    Summary TripSit

    Dextromoramide, a rare and powerful opioid analgesic approximately three times as potent as morphine with a shorter duration. Generally only seen in the Netherlands. Reported as having strange and rapid tolerance behaviour.

    Dose Information dose.wiki TripSit

    ROA Light Common Strong Heavy
    Oral 2.5-5mg 5-7.5mg 7.5-10mg 10mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, TripSit

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects
    Oral 5-15 min 3-5 hrs 1-12 hrs

    Effect Profile

    class estimate

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • No reports exist for this substance. Its effect list is the one shared by 2 other substances of the same class, so the scores below describe the class, not this compound.
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 5.4
    Moderate+ 5/10

    Strong euphoria with mild sedation and itching/nausea

    Euphoria / Warmth ×3
    9
    physical euphoria cognitive euphoria euphoria
    Analgesia ×2
    0
    Sedation / Relaxation ×1
    5
    sedation muscle relaxation
    ⚠ Itching / Nausea ×1
    4
    nausea
    View methodology →

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~35d

    Effects

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Combinations TripSit

    Cross-Check Dextromoramide with another substance

    Dextromoramide's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    💊 Pill Identifier 📘 Experience Reports 📖 TripSit 📖 PsychonautWiki
    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Dextromoramide there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "Dextromoramide (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    Dextromoramide
    Unit
    mg
    Description 
    Dextromoramide
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 2.5-5 · common 5-7.5 · strong 7.5-10 · heavy 10+

Oral duration: onset 5-15m · peak 3-5h · after-effects 1-12h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 6.25 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.