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    5,6-MDO-DMT Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data
    • 30 combo interactions documented

    Summary PsychonautWiki

    5,6-Methylenedioxy-N,N-dimethyltryptamine (also known as 5,6-MDO-DMT) is a lesser-known psychedelic substance of the tryptamine class. It is the 5,6-methylenedioxy analog of DMT.

    Perspectives

    “Nothing.”

    Effect Profile

    class estimate

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • No reports exist for this substance. Its effect list is the one shared by 3 other substances of the same class, so the scores below describe the class, not this compound.
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 6.5
    Strong 6/10

    Strong visuals with mild headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    color enhancement drifting tracers pattern recognition enhancement visual distortions brightened colour
    Headspace Depth ×3
    4
    introspection time distortion confusion
    Auditory Effects ×1
    4
    auditory distortion
    ⚠ Body Load / Somatic Effects ×1
    4
    nausea increased heart rate

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Neutral

    Combinations

    Cross-Check 5,6-MDO-DMT with another substance

    PiHKAL / TiHKAL Shulgin

    TiHKAL #31: 5,6-MDO-DMT

    “Nothing.”

    — Alexander Shulgin, TiHKAL (with 5 mg, smoked)
    →

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