5-Methylethylone Stats & Data
5-me
5-methyl-ethylone
5-methyl-bk-mdea
NPS DataHub
MW235.28
FormulaC13H17NO3
CAS1364933-82-3
IUPAC2-(ethylamino)-1-(7-methyl-1,3-benzodioxol-5-yl)propan-1-one
SMILES
CCNC(C)C(=O)c1cc(C)c2OCOc2c1InChIKey
YCLKQJDSTUZDKJ-UHFFFAOYSA-N
Chemical Class
Substituted cathinone
Psychoactive Class
Stimulant
History & Culture
5-Methylethylone emerged as a novel designer drug within the synthetic cathinone class. As a structural analogue of ethylone, it belongs to the broader category of substituted cathinones that have appeared in recreational drug markets. The compound remains poorly characterized in the scientific literature, with relatively little data available regarding its pharmacological properties or toxicity profile.
Effect Profile
Curated
Stimulant
4.2
Strong euphoria with moderate anxiety/jitters, mild stimulation
Stimulation / Energy×3
5
Euphoria / Mood Lift×2
8
Focus / Productivity×2
0
Anxiety / Jitters×1
7
Based on reports from:
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Full tolerance
1h
Half tolerance
4d
Baseline
~5d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Legal Status
| Country | Status | Notes |
|---|---|---|
| United States | Unscheduled (federally) | Not controlled under the federal Controlled Substances Act. However, it is not approved by the Food and Drug Administration for human consumption. The state of Vermont specifically lists 5-Methylethylone as a regulated drug, meaning state-level restrictions apply there despite federal unscheduled status. |